Abstract: 【Objective/Meaning】The innovation and entrepreneurship is an important way to achieve the strategic goal of Rural Revitalization. The optimization strategy of promoting the rural revitalization through innovation and entrepreneurship was discussed in this paper, in order to put forward more feasible implementation measures for the rural revitalization in the new period, and further speed up solving the issues relating to agriculture, rural areas and farmers in China.【Methods/Procedures】Through the methods such as literature review, the important driving role of innovation and entrepreneurship for rural revitalization was fully expounded, and the existing problems in promoting the rural revitalization through innovation and entrepreneurship at the present stage were analyzed in depth, including the weak overall government guidance, low contribution of “entrepreneurship and innovation”, insufficient cultivation of innovative talents, insufficient cultivation of high-quality projects, and insufficient sustainable development.【Results/Conclusions】 The results showed that: At the present stage, the innovation and entrepreneurship have achieved initial results in promoting the rural revitalization. In the future, the government should strengthen the overall planning and coordination to promote the collaborative innovation and development, promote the sinking of “entrepreneurship and innovation” education to accelerate the cultivation of innovative talents, integrate the resources to focus on the characteristics and focus on cultivating the advantageous projects, so as to lay a solid foundation for better realizing the strategic goal of rural revitalization in the 14th Five Year Plan.