Abstract: 【Objective/Meaning】Under the background of climate change, the disasters of high temperature and heat wave occurred frequently, and the health risks and social and economic losses of urban residents have become prominent. The vulnerability assessment of high temperature in cities was helpful for the identification of people at risk of high temperature and heat wave, thus to provide useful references for relevant prevention and control policies. 【Methods/Procedures】Based on the vulnerability assessment framework of “exposure-sensitivity-adaptation”, the remote sensing and GIS technologies were used to extract and integrate the spatial data such as temperature, river, vegetation, land, population, medical treatment and housing in the central city of Zhangzhou to systematically evaluate the vulnerability of high temperature in Zhangzhou City. 【Results/Conclusions】The results showed that: there were “core-periphery” structures in the spatial distribution of high temperature vulnerability, exposure and adaptability in the central city of Zhangzhou, and the vulnerability presented the spatial layout divided by water area and mountain. The high concentration of population, economy and other social factors would enhance the high temperature exposure and vulnerability of the population in such areas, where the public infrastructures were perfect, and the population was relatively strong in high temperature adaptation. The adaptability played a decisive role in the assessment of urban vulnerability to high temperature. Therefore, the government should promote relevant policies to optimize the layout of public medical facilities, increase high-temperature heat escape facilities, improve residents' ability to adapt to high temperature, and improve the pattern of urban vulnerability to high temperature.