Abstract: Considering the relationship between hotels and online travel agent (OTA) platforms, a representative hotel, Y Hotel in Quanzhou was selected as a sample for the study on influencing factors on profit ability of resort hotel in order to find the profit path based on field survey and 187 retrieved questionnaires. The results showed that three main factors influencing the profitability of the resort hotel were the tourist, OTA platform and hotel, including the individuality of the consumer’s demand, and the pursuit for low price and convenience of tourist; the profitability of hotel’s room, environment, image of the hotel staff and service level, and food quality of hotel; and the commission rate, level and functionality of OTA platform. It was concluded that the resort hotels should pay more attention to the choice of OTA partners and the improvement of service quality, and actively expand other channels For promotion.